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              首页 >> 产品 >> 抗体抗原 >> 蛋白甲基化 >> Dimethyl Arginine Antibody
              Dimethyl Arginine Antibody
              产品编号: ICP0810
              • 100.00μg
                ¥2875.00
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              详细介绍

              Dimethyl Arginine Antibody

              Catalog #

              Product Description

              ICP0810

              This antibody was raised from rabbits that were immunized with NG,NG-dimethyl arginine-KLH conjugates and specifically isolated and affinity purified using the NG,NG-dimethyl arginine antigen. The affinity purified methyl arginine antibody is useful for detection, isolation and localization of proteins with methylated arginine (asymmetric dimethylation) residues.

              Western blot of human MMRU cells with ICP0810 (A,B) plus competitive inhibition with free dimethyl arginine (C,D)
              Antigen Structure
              [Exposure:10 Milliseconds]
              IF Staining of MMRU cells
              Species
              Rabbit
              Formulation
              250μg/mL antibody stored in PBS, 50% glycerol
              Immunogen
              NG,NG-dimethyl arginine-KLH conjugates
              Purification
              Antigen-specific immunoaffinity purification with NG,NG-dimethyl arginine and adsorbed with NG-monomethyl arginine
              Specificity
              The antibody recognizes proteins with dimethylated arginine residues.  It does not cross-react with acetylated proteins or monomethylated proteins.
              Species Tested
              Human, mouse and pig
              Applications
              ELISA (1:2000); WB (1:1000); IP (5 μg/mg protein sample); IF (5 μg/mL); IHC (5 μg/mL)
              Scientific Description
              Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes, including protein trafficking, signal transduction and transcriptional regulation.
              Storage & Stability
              Product is stable for several weeks at 4°C. For extended storage, store product at –20oC. Expiration date is one year  from date of shipping if properly stored.

              Product Specific References

              1. J. Proteome Res. 2013. 12 (9): 3884-3899. doi:10.1021/pr400556c
              2. Mol. Microbiol. 2007. 65 (3): 590-606, doi:10.1111/j.1365-2958.2007.05831.x
              3. Proteomics. 2016. 16 (3): 465-476. doi: 10.1002/pmic.201400564
              4. Proteomics. 2013. 13 (7): 1059-1064. doi: 10.1002/pmic.201200477
              5. Proteomics. 2015. 15 (18): 3209-3218. doi: 10.1002/pmic.201500075
              6. J. Neurosci. 2015. 35 (37): 12890-12902. doi: 10.1523/JNEUROSCI.0246-15.2015


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